产品货号:
Z38322
中文名称:
TNFR1/TNFRSF1A抗体
英文名称:
Anti-TNFR1/TNFRSF1A Antibody (Clone#H398)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TNFR1/TNFRSF1A Antibody (Clone#H398) |
指标别名 | CD120a;FPF;p55;p55 R;p60;TBP1;TBPI;TNF R;TNF R I;TNF R1;TNF R55;TNF Receptor 1;TNF Receptor I;TNF RI;TNFAR;TNFR I;TNFR1;TNFR55;TNFR60;TNFRSF1A |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | FCM,IP,IHC,IHC-F |
基因名称 | TNFRSF1A |
克隆号 | H398 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | Recombinant full length human CD120a.The mouse monoclonal antibody H398 recognizes the extracellular domain of CD120a,a 55kDa receptor for tumor necrosis factor.The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta. |
计算分子量 | 50kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD120a/TNF R1,also known as TNFR55 or TNFRSF1A,is a 55kDa receptor for tumor necrosis factor alpha and it is expressed in most tissues.By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform.CD120a can mediate apoptosis,and function as a regulator of inflammation.Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome.The impaired receptor clearance is thought to be a mechanism of the disease. |
Uniprot ID | P19438 |
基因名全称 | TNF receptor superfamily member 1A |
蛋白名全称 | Tumor necrosis factor receptor superfamily member 1A |
推荐稀释比 | Flow cytometry:1~4μg/mL. |
相关搜索:TNFR1/TNFRSF1A抗体,TNFR1抗体,TNFRSF1A单抗,Anti-TNFR1/TNFRSF1A Antibody (Clone#H398)